The author reiterates that the transfer of public health policies to French Guyana has still not been able to fill in the gap related to delays in development of infrastructure and the lack of personnel in the social and medical establishments. The system of management for handicapped children in this French county is strongly influenced by the increasing immigrant population and by the vulnerability and instability of the administrative and socio-economic situations of those families. Furthermore, the obstacles that the professionals from the socio-medical sector must confront in their daily practice and activities are described. An analysis of their portrayals and practices permit the author to show and outline their relationships with the immigrant families who are at risk, particularly that of maintaining and suffering from the general air of stigma to which they are objected to in the Guyanese society.